Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design
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چکیده
منابع مشابه
Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design
Neuraminidase (NA) inhibitors are the dominant antiviral drugs for treating influenza in the clinic. Increasing prevalence of drug resistance makes the discovery of new NA inhibitors a high priority. Thirty-one triterpenoids from the medicinal mushroom Ganoderma lingzhi were analyzed in an in vitro NA inhibition assay, leading to the discovery of ganoderic acid T-Q and TR as two inhibitors of H...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2015
ISSN: 2045-2322
DOI: 10.1038/srep13194